In Vitro Screening and Gastro-Intestinal Simulations

ANALYSES

Determination of antibacterial activity (Minimal Inhibitory Concentration (MIC) and Minimal Bacteriostatic Concentration (MBC)) in vitro (plates) and in gastro-intestinal simulations (fermentations) for additive companies in food and feed.

SCOPE OF IN VITRO SCREENING ANALYSES AND GI SIMULATIONS

Matrix Parameter Method AC Contact
Food / feed MIC / MBC Salmonella In vitro No Geertrui Rasschaert
Food / feed MIC / MBC Salmonella fermentor No Geertrui Rasschaert
Food / feed MIC / MBC Campylobacter In vitro No Geertrui Rasschaert
Food / feed MIC / MBC Campylobacter fermentor No Geertrui Rasschaert
Food / feed MIC / MBC
Other pathogens
In vitro No Geertrui Rasschaert
Food / feed MIC / MBC
Other pathogens
fermentor No Geertrui Rasschaert

CONTACT

Geertrui Rasschaert, Marc Heyndrickx

REFERENCES

W. Messens, J. Goris, N. Dierick, L. Herman and M. Heyndrickx. 2010. Inhibition of Salmonella typhimurium by medium-chain fatty acids in an in vitro simulation of the porcine cecum. Veterinary Microbiology 141: 73-80.

A. Smet, G. Rasschaert, A. Martel, D. Persoons, J. Dewulf, P. Butaye, B. Catry, F. Haesebrouck, L. Herman and M. Heyndrickx. 2011. In situ ESBL conjugation from avian to human Escherichia coli during cefotaxime administration. J. Applied Microbiol. 110: 514-549.